The NIH Director's Early Independence Award 2019 call for applications is closed. The previous call is below for your reference only.  This call for applications is scheduled to be updated in 2020 and the deadline is anticipated to be in June of 2020. Please check the ECOR website and your emails from MGH Research News for updates. Click here to sign up to receive MGH Research News.

Gabrielle's Angel Foundation for Cancer Research 2021

MGH Internal Pre-proposal Deadline

Thursday, June 17, 2021 – 5:00 PM



"For over two decades, Gabrielle’s Angel Foundation has provided significant financial support to some incredibly promising physician scientists, who are applying novel and state-of-the-art techniques to address fundamental problems in the genesis and treatment of blood related cancers. Since 1996, the Foundation has committed more than $37 million in grants to over 300 junior faculty members at the nation’s leading institutions. These grants continue to be a sign of excellence and represent support for many of the most exciting new scientific ideas in blood cancer research.

Gabrielle’s Angel Foundation remains committed to funding innovative, translational proposals and to supporting promising independent early-career investigators, rather than well-established, senior scientists.

MGH is eligible to nominate a maximum of two candidates - one in the mainstream/conventional medical research category and one in the integrative medical research category.


Mainstream/Conventional Category:

Applicants should be independent MD and/or PhD Assistant Professors who have been in their current position for no longer than five years. 


Integrative Category:

Applicants should be independent MD and/or PhD Assistant Professors or Associate Professors. The length of time that an applicant has held their current faculty position is not relevant in this category. 

The Foundation seeks to support Integrative research projects that explore evidence-based complementary interventions, optimize the manner in which mainstream care is delivered and improve the lives of those living with cancer, specifically the hematologic malignancies.

The Foundation seeks to support clinical trials and/or pre-clinical research which address reducing patients’ physical and emotional distress during or after cancer therapy."




The award will be for three-year period at $75,000.00 per year (including 10% IDC), contingent on the submission of acceptable annual progress reports.

For MGH investigators selected through a competitive process as the institutional nominee for any limited submission funding opportunities, in situations in which the grant will bring in less than 15% indirect cost (IDC), ECOR will cover the IDC gap up to a maximum of $50,000 per year. In order to optimize the distribution of limited ECOR funds across the MGH research community, it is expected that PIs and departments will work together to cover the remaining IDC shortfall.




MGH Internal Pre-Proposal Deadline:  Thursday, June 17, 2021 at 5pm

Notification to MGH Candidate: Early/Mid July

Sponsor Deadline: Friday, August 27, 2021 




At the time of application, the applicant:

  • Must have a full-time primary appointment at MGH
  • Must be an MD or PhD
  • Must be appointed an Assistant Professor (Associate Professors may also apply for *Integrative* projects only)
  • Have instituional support in form of tenure track OR be an independent junior faculty member
  • Have held their current position no longer than five years (for conventional projects only)
  • Clearly state that they have both independent research projects and independent resources
  • Have preliminary results and/or publications from their independent laboratory
  • At Mass General Hospital we believe that because of diversity we excel.  Therefore, women and research investigators who are considered underrepresented in academic medicine (UIM) are strongly encouraged to apply.



  • Research must be compelling with firmly grounded scientific rationale and high-quality relevant methodology.
  • Proposals must reflect a solid grasp of the field and employ pragmatic research methodology and design.
  • Proposals will be evaluated for creativity, originality and scientific rigor.
  • Proposals based on promising preliminary data will be favored.
  • Applicant’s prior experience and competencies will be assessed – for integrative applications only, Associate Professors as well as Assistant Professors are invited to apply.



The MGH internal preliminary application must include the following 5 items:  

1. Project Title

2. Research Category. Please select the research category: Mainstream/Conventional or Integrative

3Assistant Professor Appointment. List the month, day, and year that you were first appointed an Assistant Professor. (For Mainstream/Conventional projects only)

4. Statement of Independence (500 words) including:  

  • A description of the Institution’s level of commitment to the Applicant, including all department support, and the long-term plan that is in place for his/her independent, professional development. 
  • Size of the Applicant’s start-up package including any salary support.
  • Amount of lab space under the applicant’s control 

5. Research Proposal (2-3 pages; PDF only)

6. Biosketch of the applicant in NIH format (not a CV).  Click here for a sample NIH biosketch.

7. Other Support, a list of other current and pending support sources, in the NIH format.  If the applicant does not have other current or pending support sources, please indicate “none” when applicable.  Click here for a sample Other Support list in the NIH format.

8.  Letter of recommendation from Department, Unit, or Division Chief (address letters to ECOR Review Committee).  (2 pages max). This letter should include details regarding the department’s commitment to the applicant's independent research career.




  • Use margins of 0.5 inches or greater
  • Use 11pt font size or greater.
  • Upload PDF documents only.  Limit characters to A-Z and 0-9 when naming PDF documents.  Do not use periods, commas or dashes in the file name.




ECOR accepts all applications online via the MGRI Online Grant Management Portal.  The system has been designed to allow users to:

  • Create a personal profile, which will auto-populate your future ECOR applications
  • Assign a delegate to submit applications on your behalf (optional)
  • View current calls and apply to open opportunities 
  • Save and edit current applications in progress
  • Submit completed applications.

Instructions for Applying Online:

1.        Create your account: Log in using your Partners credentials and fill-out the profile information.

2.        Complete the application: Once your profile is complete, you will automatically progress through the online application. If you cannot complete the application at one time, “save” the application and return to it at a later time to finish. Before submitting your application, you will have the ability to make changes to the application.

3.        Submit your application: Once you have completed the application click on the “submit” button at the bottom of the page. Once you submit it, you will not be able to make further changes unless you send a request to ECOR (note that once the deadline passes, requests to make changes will not be accepted).


Useful tips:

  • To avoid losing your work, remember to save frequently
  • You can only upload PDF documents
  • If you previously created a profile, please ensure your information is current prior to submitting an application.

  Click 'Apply' below to begin the application.




If you have any questions, please email ECOR.

To review the Gabrielle's Angel guidelines and the FAQ, please click here.

To view a list of past awardees, click here