Research News - June 24, 2022

 

         
   
 
  June 24, 2022
 
ANNOUNCEMENTS
 
 

1. MGH Research Job Board
2. June 30 booster shot deadline: What you need to know
3. SAS & Biorender Licensing Available

4. Revised Changes to CCM Housing and Research Support
5. Call for 2022 SRTP Faculty Abstract Reviewers & Final Presentation Panelists 

 
EVENTS
 
 

1. Fun Fridays – Vinyasa Yoga
2. Presentation Skills Series:“10 Truisms for Developing and Delivering Outstanding Presentations”
3. MGH-Broad Working Group Science Meeting
4. MGRI Summer Science Slam
5. MGH Lab Managers’ Discussion Group Meeting with Supply Chain
6. Grant Administration & Management Course Session 3: Hiring and Conflict Management
7. Chester Pierce Research Society Speaker Series

 
FUNDING OPPORTUNITIES
 
 

1. COVID Funding Opportunities
2. Interim Support Funding
3. NIH Director’s Early Independence Awards
4. The Chong Jin Park Innovative Early Career Pilot Award in Aging and Palliative Care & The Ki Sub Joung Innovative Junior Faculty Pilot Award in Aging and Palliative Care 2022
5. ADDR-Harrington Scholar Award
6. Brain Care Score Implementation
7. T32 Postdoctoral Program to Enrich Translation and Multimodal Research in Alzheimer’s Disease and Related Dementia (PET/MR in ADRD) - T32 AG066592
8. Arvinas Launches Global Early Career Researcher Award and Announces Call for Nominations
9. Limited Submission Funding Opportunities
10. Foundation Funding Opportunities

 
In Case You Missed It
 
  Reminders of recently posted funding opportunities, deadlines and events
   
  ANNOUNCEMENTS
   
  1. MGH Research Job Board
 

Are you looking for a new opportunity within the Mass General Research Institute or hoping to promote a newly posted job within your department? Check out the Research Job Board, powered by the Division of Clinical Research! All members of the community are able to submit postings or apply for positions. 

Click here to learn more.

   
  2. June 30 booster shot deadline: What you need to know
 

For those who completed their primary vaccine series between August 1, 2021 and January 1, 2022, a booster must be received by June 30, 2022. Those who are not yet compliant with our booster vaccine policy will begin receiving email notifications this week. 

How employees can receive the vaccine
Occupational Health is currently offering Pfizer COVID-19 vaccines at the following Occupational Health Clinics: Massachusetts General Hospital, Brigham and Women’s Hospital, Brigham and Women’s Faulkner Hospital, Newton-Wellesley Hospital and Salem Hospital. Appointments for the month of May can be made here.

These same Occupational Health locations will offer clinics in June, providing Pfizer booster vaccines for eligible workforce members. Appointments can be made through the Vaccine Clinic Bookings links on The Pulse. 

Individuals who need a Johnson & Johnson or Moderna booster are encouraged to leverage a location in their local community. There are many sites, including CVS and Walgreens, offering free booster shots. Visit vaccines.gov, mass.gov or vaccines.nh.gov to find a location near you. You can also text your zip code to 438829 or call 1-800-232-0233. 

   
  3. SAS & Biorender Licensing Available
 

Discounted SAS statistical licenses are offered through the ERIS Research Computing Core. The price for a SAS Citrix or SAS Server license dropped to $240/license per year/platform and can be accessed from multiple devices. To purchase a new license or renew a Desktop license, please visit the ERIS Research Computing Core Request Catalog: rcservices.partners.org (and log in with MGB Username and Password). Please read about the different offerings of discounted SAS licenses at rc.partners.org/sas. Please contact us at rcc@partners.org with any questions. 

BioRender licenses are available at a discounted rate through the Research Computing Core. BioRender is a web application that can be used to create scientific figures, diagrams, and illustrations from a scientifically accurate image library, all in a matter of minutes. Using a simple drag and drop model, BioRender will save you time, so you can focus more on the science and less on illustration. BioRender requires no installation and you may log into your account on any computer, to access the BioRender portal. For more information on BioRender, go to the Research Computing Core's software page or order now at rcservices.partners.org (MGB login required). All questions may be directed to rcc@partners.org

   
  4. Revised Changes to CCM Housing and Research Support
 

This COVID Pandemic Emergency Response Plan (ERP) Guidance applies to all research staff housing animals in CCM facilities. All MGH Guidelines and Policies for Return to Onsite Research and on-going COVID-related requirements must also be followed in all animal areas. Critical information can be found on the Animal Program page on the MGRI Coronavirus website

PPE Requirements in CCM Facilities:
Because of the on-going potential risk to our animal population as well as the risk of being short staffed due to absences from personal illnesses, for now CCM will continue to require masks in our facilities. Entrance hallways, airlocks, etc. have appropriate signage announcing that masks are (still) required. 

Remember that everyone entering CCM facilities should be wearing a mask upon entry. You should make sure to use hand sanitizer before touching any door handles, PPE, cage set-ups or other equipment located in the CCM facility. Required PPE should be donned before entering the animal facilities. Proper microisolator technique, especially dipping gloves in between handling cages, when followed can prevent potential contamination. All carts and cages used or brought into the animal facility must be wiped down completely with sani-wipes or other provided disinfectants in the airlock or at the PPE stations prior to entering the animal facility. 

UPDATE: CCM HUSBANDRY & RESEARCH SUPPORT RESTRICTIONS:
CCM continues to see escalating staffing shortfalls. We currently have 3X pre-pandemic number of vacancies in our frontline staff as well as the highest attrition rate of 39% experienced in the last 20 years. Our ability to continuously provide adequate care and oversight during these staffing shortages has been offset by a slow census growth until recently (early May 2022). Over the past month, however, our rodent census has started to climb to 30,000 cages or more and we also continue to receive requests for help from the labs for additional research support services. This growing demand on CCM staff for both husbandry, research support and regulatory oversight are contributing to more concerns in our ability to maintain a regulatory compliant animal care and use program. Therefore, we are bringing back the opportunity for research staff to assist with CCM through our Research Staff Volunteer Program. 

Part 1: Research Staff Volunteers Needed: Sign-up Process.
CCM will again be calling on the research community to assist in animal care-related (operational) support. Our improved Volunteer Clearance and Utilization System will allow us to schedule research volunteers more efficiently, effectively and with transparency. We are looking for help from MGRI staff with current animal facility access and availability to fill out our NEW volunteer portal here

We appreciate all assistance provided by the research community thus far. We look forward to continuing this partnership to ensure we are able to provide the best possible animal care and supporting critical research needs. All volunteers will receive a 60-min training on the tasks that they will be assigned to perform as well as hands-on training support in each CCM facility. You will receive a notification about the training after you complete the volunteer portal. 

Part 2: Utlization of Off-Site Rodent Housing – CRL Update.
CCM is also working with Charles River Laboratories (CRL) to relocate up to 1000 rodent breeding cages in isolation at their Wilmington facility. This is being done to right-size the current workload to available resources for on-site (MGH) husbandry and research support while utilizing off-site partners (CRL) who provide the needed services at the highest quality at a competitive price. Breeding services (included in their per diems) can be provided and experimental animals can be shipped to MGH similar to their own mouse model product lines (same transportation schedule). The costs of housing animals off-site will be similar to the MGH per diem. It is also imperative that PIs and Lab leadership evaluate the number of different strains needed for current research initiatives and make decisions to cryopreserve lines that are important but not currently needed. 

Lastly, CCM will be conducting a rodent colony breeding management workshop in late July to help research teams determine how to manage their in-house rodent colonies as efficiently as possible. More will be announced about this next month. 

Satellite Housing Facilities
All satellite housing facilities with Option “A” CCM contractual services will follow this guidance. For Option “B” and “C” CCM contract laboratories, lab management is asked to adopt these practices or provide a comprehensive plan that similarly demonstrates compliance with these guidelines and policies. To continue to protect the animals and assure MGH staff safety (allergen exposures, etc.), satellite facilities must follow PPE requirements. Lastly, emergency response plans must specific address how staffing shortages will be managed to ensure husbandry and care of animals meets regulatory requirements. Please submit alternate practice requests to IACUCCompliance@mgh.harvard.edu. 

IMPORTANT REMINDER:
Animal Welfare Oversight 

Please review and consider the following: 

  • Protocol compliance is still required even when emergency response plans are in place; animal welfare cannot be compromised even if that means having to end an experiment early during to staffing or other challenges; 
  • Put contingency plans in place now, in case staffing is impacted by COVID:
    • Only staff approved on the IACUC protocol can do research on animals; add back-up staff now and make sure they have access to, and are familiar with, the details of the protocol. Note, OHS is extremely busy and clearance for animal research may take extra time; 
    • Only staff proficient in the procedures described in the protocol should perform those procedures; 
    • All staff doing work must have access to the necessary training, information, tools and materials – this includes the protocol but also medications & treatments, controlled substances, tools and equipment. A surgery should not be performed if there is no access to analgesic medication as described on the protocol, for example; 
    • Review and train staff on communication plans and hand-off strategies; assuming someone can just pick-up an experiment where someone else left-off has not proven to be successful for many groups; 
    • Animals must be monitored in-person, not remotely, unless specifically approved in the IACUC protocol. 
  • Don’t start experiments unless you can ensure the necessary oversight and care as described in the protocol:
    • CCM cannot be relied on as a back-up if staff can’t make it to work; 
    • Shipping and other delays may impact your inventory of drugs, medications, etc. Please, do not start a survival surgical procedure assuming your analgesics will be delivered on time for post-procedural care. Only start work if you have everything and everyone you need already in place. 
  • Satellite Facilities: please review and adjust your emergency response plans if needed; please make sure everyone is trained on their role & responsibilities, and on the communication plan to ensure animal care and oversight; 

COVID Risk to CCM Animal Health:
The laboratory animal medicine community is still evaluating the impact of SARS-CoV-2 on our animal colonies. While it remains unclear the exact risk, several species, including mice, ferrets, hamsters, dogs, cats and nonhuman primates, have been found to test positive for the virus after exposure or are currently being tested as appropriate animal models. CCM continues to encourage limited movement of animals outside of CCM facilities, except for terminal procedures, and when required, be performed in CCM-provided or IACUC-approved transport containers. As always, proper PPE must be worn when manipulating animals whether inside CCM facilities or in the laboratory areas. 

CCM’s COVID-related Behavioral Expectations
All CCM facilities and satellite housing facilities with Option “A” CCM contractual services will follow this guidance. For Option “B” and “C” CCM contract laboratories, lab management is asked to adopt these practices or provide a comprehensive recovery plan that similarly demonstrates compliance with these guidelines and policies. These recovery plans should be considered a supplement to your Emergency Response Plans (ERPs) for Pandemics and should be submitted directly to the IACUC to assure continued animal welfare regulatory compliance. 

Throughout the COVID19 response, CCM has been committed to three goals: 

  1. Ensuring that the animals in our care continue to receive our standard high quality of care 
  2. Ensuring that we provide a workplace that is as safe for MGH employees as possible 
  3. Ensuring that critical research programs using animals continue while fully adhering to goals 1 and 2. 

If you have additional questions regarding animal research associated with your ERP plans, please email us. For IACUC-related questions, please email IACUC@mgh.harvard.edu and for CCM questions, feel free to share your feedback via the new CCM Feedback Portal

   
  5. Call for 2022 SRTP Faculty Abstract Reviewers & Final Presentation Panelists!
 

The Summer Research Trainee Program (SRTP) has served as the Center for Diversity and Inclusion’s (CDI) student pipeline efforts start. The goal of the program is to inspire students who are underrepresented in medicine (UiM) to consider careers in academic medicine by immersing them in cutting-edge research opportunities. 

A select group of 30 graduate and medical students were accepted into the 2022 summer program and will have a personalized research experience conducting novel research in a vast variety of biomedical science and health policy research areas. Along with attending workshops and seminars students are required to prepare an abstract and an oral presentation of their research project during the eight-week program. MGH faculty abstract reviewers and student final presentation panelists are needed to review and provide feedback. 

If you are interested in being a student Abstract Reviewer or Final Presentation Panelist, please review the dates below and provide your availability by clicking the appropriate link. CDI will assign a date/time to you based on your availability. 

If you have additional questions or concerns, please email Karen Osborne Green (kosborne@partners.org) or CDI (cdi@mgh.harvard.edu). 

Abstract Reviewers: 

  • Review 3 – 4 abstracts & discuss feedback with students via Zoom 
  • Zoom meeting options (1 hour/15 min per student):
    • July 12: 8 - 9a, 11:00 am - 1:00 pm, 4:30 - 6:30 pm Or 
    • July 13: 8 - 9a, 11:00 am - 1:00 pm, 4:30 - 6:30 pm 
  • Provide your availability: https://doodle.com/meeting/participate/id/epYlglXa 

Final Presentation Panelists 

  • Listen & score student presentations & provide feedback o Student final presentations schedule:
    • July 14 (1 student): 1:00 pm – 1:30 pm 
    • July 27 (14 students): 9:00 am – 1:00 pm 
    • July 28 (13 students): 1:00 p – 6:30 pm 
    • August 3 (2 students): 12:00 pm – 1:00 pm 
  • Provide your availability: https://doodle.com/meeting/participate/id/aM8xjn1e
   
   
 
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  EVENTS
   
  1. Fun Fridays – Vinyasa Yoga
 

Friday, June 24, 2022, 12:00 – 1:00 pm, Zoom 

This is the last Fun Friday until September! 

Sponsored by the Center for Faculty Development’s Office for Well-Being 

Vinyasa Yoga is a vigorous yoga class that moves through poses at the pace of your breath. This class is designed for all levels; modifications are offered, allowing you to tailor the class to your ability and your body’s needs. The sequence of each class will build towards a challenging peak pose(s). Appropriate for both the beginner and advanced practitioner, this class will be stimulating and fun! Props: Please wear attire appropriate for exercise and have a yoga mat. Blocks, blanket and strap are optional. 

Facilitator: Masha Leuner. A world traveler and long-time yoga practitioner, Masha holds a BA/MA from Brandeis University and an MBA from NYU Stern School of Business. As a career-driven marketer in a high-paced corporate environment, Masha always wondered what an alternative life path would be like. After the birth of her second child, she decided to let it all go, took Yoga Teacher Training, and in 2017 became a certified yoga teacher. Masha’s natural yearning for learning has led her to take multiple advanced trainings, receive certification in Yoga for Osteoporosis and Back Pain, as well as continue to perfect her teaching in Vinyasa. She teaches full-time at Coolidge Yoga in Brookline and is enrolled in advanced 300hr certification program at Down Under Yoga. 

Click to register 

   
  2. Presentation Skills Series:“10 Truisms for Developing and Delivering Outstanding Presentations”
 

Tuesday, June 28, 2022, 12:00 pm – 1:00 pm, Zoom 

Provided by: Mass General Brigham and MGH Center for Faculty Development 

Session 4 of the Presentation Skills Series 

Love 'em or hate 'em, your basic didactic presentation isn't going anywhere. If you've been asked to give a lecture or talk, or if you're interested in improving talks that you have already developed, this session is for you. We will discuss 10 truisms that shape the development of outstanding academic presentations, with a focus on how to design presentation materials that facilitate learning. How to communicate content, what visuals to include (or delete), and how to align your presentations with the particular requirements of virtual platforms, will all be discussed. 

Learning Objectives:
Upon completion of this activity, participants will be able to: 

  • Identify "truisms" that shape the development and delivery of outstanding academic presentations 
  • Design high-quality slides that focus on learning 
  • Revise presentations to better align with particular requirements of virtual delivery 

Target Audience: This activity is intended for faculty and faculty trainees.
Course Director: Miriam A. Bredella, MD 

Presenter: Emily Green, PhD, MA is the Assistant Dean for Faculty Development at The Warren Alpert Medical School of Brown University, and the author of the book, Healthy Presentations: How to Craft Exceptional Lectures in Medicine, the Health Professions, and the Biomedical Sciences. An educator by training, and a secret fan of lecturing as a teaching modality, Emily has made her career in medical student and faculty development over the past 20 years. In her current role she oversees the design and delivery of non-clinical professional development initiatives around teaching and learning, diversity and inclusion, faculty wellness, career development, research and scholarship, and leadership skill development. 

ACCREDITATION
Mass General Brigham is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. 

Mass General Brigham designates this live activity for a maximum of 1 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Click to register 

   
  3. MGH-Broad Working Group Science Meeting
 

Tuesday, June 28, 2022, 2:00 pm, Simches 3.110 & Zoom 

Please join us for the next meeting of the MGH-Broad Working Group, Tuesday, June 28 at 2:00 p.m. 

Our speakers will be Daniel Haber, MD, PhD, Director of the MGH Cancer Center and Kurt J. Isselbacher Professor of Oncology, Harvard Medical School, and Mario Suva, MD, PhD, Associate Professor of Pathology, MGH, Broad Institute Member, Janet and William Ellery James MGH Research Scholar, and co-Leader DF/HCC Neuro-Oncology. 

As a reminder, this working group brings together over 100 MGH-Broadies to share ideas for improving and expanding Broad-MGH collaborations. Everyone from your lab is welcome to join us, and we hope you will spread the word to your colleagues.

Our spring meeting will be in-person at the Simches Auditorium 3.110 with a Zoom option. 

Join Zoom Meeting: https://partners.zoom.us/j/83120424831?pwd=TERYay9IOTVNejZ1QVU2ZEhEVk5JUT09
Meeting ID: 831 2042 4831
Passcode: 006632
Dial by your location: +1 646 876 9923 US (New York) 

   
  4. MGRI Summer Science Slam
 

Tuesday, June 28, 2022, 5:00 – 7:00 pm, Bulfinch Tent 

I scream, you scream, we all scream for SCIENCE! 

The Science Slam is presented by the Office of the Scientific Director and the Center for Diversity and Inclusion.  

Register to take the mic and slam your science at our first in person Science Slam in over two years! MGRI Science Slams are fun, informal science communication events where researchers are challenged to explain their science in layman's terms in three minutes or less. (You can see some previous Slams on our blog!) 

We encourage you to think out-of-the box in terms of presentation format (i.e., no PowerPoint) but we encourage you to get creative with props, pictures, everyday household items or something we haven't even thought of yet. All Slammers will receive a gift for participating! 

Ice cream will be served for everyone who attends. If you have summer interns in your research program, please encourage them to attend and participate. 

This is a free event open to all members of the MGRI community. If you have any questions, you can email Coleen Cunningham at ccunningham8@mgh.harvard.edu

Click here to register. 

   
  5. MGH Lab Managers' Discussion Group Meeting with Supply Chain
 

Wednesday, June 29, 2022, 11:00 – 12:00 pm, Zoom 

Join the Lab Managers’ Discussion Group for a discussion and Q&A with members from Supply Chain. 

If you have questions or comments you would like to submit in advance of the meeting, please fill out the form: Supply Chain Queries

Join URL: https://broadinstitute.zoom.us/j/903351769?pwd=WkJKellVSDBKd2tlb2IrQncyaG9Zdz09
Meeting ID: 903 351 769
Passcode: 638795
One tap mobile: +16468769923,,903351769#,,,,*638795# US (New York)
Dial in: +1 646 876 9923 US (New York) 

   
  6. Grant Administration & Management Course Session 3: Hiring and Conflict Management
 

Thursday, June 30, 2022, 2:00 – 3:00 pm, Zoom 

Sponsored by the Office for Research Careers 

The Office for Research Careers is launching a NEW Grant Administration and Management course for junior PIs. The course aims to provide more guidance and familiarity in grant administration and management (i.e., allocating % effort, managing budget expenditure, hiring, and changing research direction). This course will provide junior PIs with practical tips that will help them efficiently manage their grants, research, and lab. Each session will have ample time for PIs to ask questions. 

Session 3 - (June 30): Hiring & Conflict Management facilitated by Lotfi Merabet, PhD, MPH, Associate Professor of Ophthalmology at HMS; Director, Laboratory of Ophthalmology at MEEI 

Click to register for Session 3
Click here for info and the recording of Session 1
Click here for info and the recording of Session 2 

   
  7. Chester Pierce Research Society Speaker Series
 

Wednesday, July 6, 2022, 4:00 – 5:00 pm, Zoom 

Functional Neurological Disorder: Research Insights Bridging Physical & Mental Health 

David L. Perez, MD, MMSc
Departments of Neurology and Psychiatry
Director, Functional Neurological Disorder Unit & Research Group
Associate Professor in Neurology, Harvard Medical School 

The Chester Pierce Research Society (CPRS) is sponsored by the Center for Diversity and Inclusion (CDI). CPRS is a speaker series named in honor of MGH's late Professor Emeritus in Psychiatry, Chester Pierce. Dr. Pierce was the first and most senior African-American physician-scientist at MGH. CPRS is designed to promote diversity and health equity by featuring the novel research of investigators to the MGH community.

Click here to RSVP. 

   
   
 
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  FUNDING OPPORTUNITIES
   
  1. COVID Funding Opportunities
 

Please visit the MGB web page for COVID funding opportunities that provides a central database for researchers to view open and competitive funding announcements. 

We have aggregated opportunities from federal and private funding sources including NIH, DoD, CDC, EPA, foundations, and more. The database defaults to sorting by award amount and can also be sorted by deadline or filtered by research focus. 

Upcoming deadlines:
 

Recently added: 

  • No new additions 
   
  2. Interim Support Funding
 

The Executive Committee on Research (ECOR) is now accepting applications for Interim Support Funding. 

What are they?
Interim Support Funding The Interim Support Funding (ISF) Program is open to Principal Investigators during a lapse or delay in their research funding from the NIH or another Federal agency (e.g., the National Science Foundation, the Department of Defense). Investigators must have applied for independent, long-term support (R01, R21, U01 and P01). The intent of the program is to rescue strong scientific programs that are in need of bridge funding in order to sustain their research. Applications will be accepted regardless of percentile or score, including applications that were not discussed. 

When is the deadline?
Monday, August 1, 2022 - 5:00 PM 

How do I learn more and apply?
Interim Support Funding - Click here 

   
  3. NIH Director’s Early Independence Awards
 

Preliminary applications are now being accepted by the Executive Committee on Research (ECOR) for the NIH Director’s Early Independence Awards. 

What are they?
The NIH Director’s Early Independence Award Program supports exceptional investigators who wish to pursue independent research directly after completion of their terminal doctoral/research degree or clinical residency, thereby forgoing the traditional post-doctoral training period and accelerating their entry into an independent research career. The Early Independence Award is intended for these select junior investigators who have already established a record of scientific innovation and research productivity and have demonstrated unusual scientific vision and maturity; typical post-doctoral training would unnecessarily delay their entry into independent research.” 

MGH is eligible to nominate two candidates for the NIH Director’s Early Independence Award. 

When is the deadline?
MGH internal pre-proposal: Tuesday, June 28, 2022 – 5:00 PM 

How do I learn more and apply?
Click here to for more information and to apply for the nomination. 

   
  4. The Chong Jin Park Innovative Early Career Pilot Award in Aging and Palliative Care & The Ki Sub Joung Innovative Junior Faculty Pilot Award in Aging and Palliative Care 2022
 

Applications are now being accepted by the Mongan Institute Center for Aging and Serious Illness for the The Chong Jin Park Innovative Early Career Pilot Award in Aging and Palliative Care & The Ki Sub Joung Innovative Junior Faculty Pilot Award in Aging and Palliative Care 

What is it?
The Mongan Institute Center for Aging and Serious Illness supports innovative, transdisciplinary research that leverages MGH’s and the broader community’s strengths to improve the well-being of older adults and those with serious illness. The Center for Aging and Serious Illness Early Career Pilot Awards in Aging and Palliative Care will support innovative applied clinical research or implementation pilot project(s) (T3-4) focused on improving the evidence base for aging or serious illness care. This award will fund initial pilot work to provide data and planning for an externally funded, full-scale project grant (e.g., K award, R01, PCORI etc.). Applicants who hold a full-time appointment in any MGH Department, are pursuing a research career, and meet the eligibility criteria below are encouraged to apply. 

The Chong Jin Park Innovative Early Career Pilot Award in Aging and Palliative Care will support research focused on achieving I health equity and improving the lives of older people and or those with serious illness through research in population and health care delivery science. The Ki Sub Joung Innovative Junior Faculty Pilot Award in Aging and Palliative Care will support research focused on improving the lives of older people and or those with serious illness, with an emphasis on the care of those living with cognitive impairment or their caregivers. 

How much is the award?
The award is $50,000 for one year plus 20% indirect costs and is effective October 1, 2022. 

When is the deadline?
August 11, 2022 by 5 pm EDT 

How do I learn more and apply?

   
  5. ADDR-Harrington Scholar Award
 

 ** Ph.D. or M.D. or equivalent required for eligibility. Open to researchers in the U.S., U.K. and Canada. 

Call Opens: June 1
Letters of Intent (LOI) Due: July 18, 2022 

Harrington Discovery Institute (HDI) and the Alzheimer’s Drug Discovery Foundation (ADDF) invite you to submit an LOI for the 2022 ADDF-Harrington Scholar Award. This grant is designed to accelerate the translation of academic discoveries into medicines for treating, preventing, or curing patients with Alzheimer’s disease and related dementias. Of particular interest are targets related to neurovascular health and epigenetics. Researchers working on drug development programs that are relevant to, but not presently focused on, the Alzheimer’s field are encouraged to apply. In addition to grant funding, HDI provides guidance and oversight in all aspects of drug development, while taking no rights to intellectual property, which is retained by you/your institution. 

To learn more about the award, click here

To submit an online application, go to ADDF’s funding system and create an account. 

Click here to view the FAQ. 

Application questions?
Contact grants@alzdiscovery.org or HDIQuestions@HarringtonDiscovery.org

Scientific inquiries?
Contact Meriel Owen, PhD, ADDF at mowen@alzdiscovery.org

   
  6. Brain Care Score Implementation
 

About the McCance Center for Brain Health
The McCance Center for Brain Health is a clinical and research center founded to maximize human potential through better brain health. Through its ground-breaking research, clinical innovation, and global collaborations, the Center aims to reduce the incidence of common brain diseases through effective primary prevention. 

About the McCance Brain Care ScoreTM
A large body of evidence links a set of modifiable factors with risk of stroke, dementia, depression and other brain diseases, offering a substantial opportunity for prevention of common brain diseases in primary care. Yet, unlike heart care and cancer prevention, preventive brain care has traditionally not been incorporated into routine primary care. 

Developed in the Center’s clinical-translational program, the McCance Brain Care Score™ (BCS) answers a key question with scientific validity: “What can I do to take good care of my brain?” Designed to be implemented in health care settings anywhere, the BCS compiles the modifiable risk factors that impact brain health and provides a mechanism for anyone to track and prioritize their brain care through an approach that focuses on steps any of us can take. 

For more information on the BCS, please click here

Opportunity Snapshot
Towards its aim to integrate brain care into routine medical care, the McCance Center is investing in the development of innovative methods for the implementation of the McCance Brain Care Score™ in primary care practices across diverse communities. The center is seeking proposals from partners with expertise in implementation science to propose novel approaches for catalyzing the uptake of the BCS by practitioners, patients, payors, and policymakers.

With the long-term goal of improving brain health, proposals will need to address the shorter-term goal of increasing engagement in brain care across communities. Specifically, we encourage proposals to address: 

  • Strategies for engaging communities, particularly those impacted by healthcare disparities. e.g. Patient and Community Advisory Committees 
  • Mechanisms for sustained behavior change among patients, practitioners, and healthcare systems. 
  • Establishing measurements of success of engagement by these groups 
  • Integration of digital health and technologies 

Criteria for Review:
Successful applications will have a timeline with milestones that culminates in the submission of a competitive federal grant proposal (e.g. NIH, PCORI, etc) within 12 months of the award of this SPARC. Criteria for review will include: applicants’ track record of successful funding, the closeness of the proposed aims to the McCance mission, the feasibility of the proposal to yield a competitive grant application. 

Application Instructions:
The proposal: 

  • Limited to two pages 
  • 12-point Times New Roman font 
  • 1” margins all around, single-spaced (excluding references). 
  • Sections of the proposal:
    • Specific Aims 
    • Background/Introduction 
    • Methods 
    • Significance 
    • References (not counted towards the 2-page limit) 
  • Provide information on your Team. Please include NIH biosketches for all participating investigators 
  • Please include a separate budget justification (limit to one page). 

The deadline for proposal submission is July 15. Review will be completed and decisions announced by July 31. Please send proposals to Dr. Akshata Sonni, Scientific Program Director, McCance Center at asonni@partners.org

Eligibility Criteria
Any applicant eligible to serve as a Principal Investigator on a federal grant application is welcome to apply for this award. In a separate document and as indicated above, applicants must also provide the bios of the key team members on the project, as well as information on any collaborators or corporate/public sponsors that will be engaged as a part of the project. If applicable, please demonstrate how these collaborators and partners have already been engaged. 

Award Amount
Budgetary requests of up to $150K for one year will be considered 

Duration of Award
1 year 

Selection 

Proposals will be reviewed by a committee appointed by the McCance Center, which will make recommendations to the McCance Center Co-Directors, who will make the final determination. 

   
  7. T32 Postdoctoral Program to Enrich Translation and Multimodal Research in Alzheimer’s Disease and Related Dementia (PET/MR in ADRD) - T32 AG066592
 

The primary mission of this program is to promote the development of a diverse, translational research workforce that is capable of participating and/or leading cross-disciplinary team science relevant for the treatment and prevention of Alzheimer’s disease and AD-related dementias. The trainee will pursue a targeted research project under the mentorship of world-class researchers in the Harvard research community in three key areas:
[1] biology of aging and neurodegeneration;
[2] data sciences, computational biology, statistics, math/engineering/physics;
[3] drug discovery and development 

Most T32 faculty are within the MGH Martinos Center for Biomedical Imaging and/or Massachusetts Alzheimer’s Disease Research Center. Training includes targeted coursework, didactic lectures, and a dedicated T32 lecture series. General training includes research conduct, diversity and inclusion, mentoring, career development, and grant development activities. 

Eligibility: PhD, MD, MD/PhD and U.S. citizen or permanent resident (see NIH PAR-18-524), with rolling admission for 4 training slots. Our goal is to recruit a truly diverse T32 trainee pool that is highly representative of URM and women trainees. 

Additional information: Please see https://pricelab.martinos.org/t32-adrd/ for further information including application instructions. Please submit questions to: Krystal Whitfield (T32 Administrative Contact) at T32ADRD@mgh.harvard.edu

   
  8. Arvinas Launches Global Early Career Researcher Award and Announces Call for Nominations
 

In honor of 20 years of targeted protein degradation, Arvinas announces $25,000 monetary award to recognize an up-and-coming researcher in the field of targeted protein degradation 

Arvinas, Inc., a clinical-stage biotechnology company creating a new class of drugs based on targeted protein degradation, today announced a global call for entries for their inaugural Early Career Research Award. This award will recognize up-and-coming researchers bringing innovation, new approaches and creative thinking to advance the field of targeted protein degradation; acknowledging their dedication and commitment to this therapeutic approach toward otherwise intractable disease targets. The winner will receive a $25,000 monetary award and will be recognized and formally presented with this award at the 5th Annual Targeted Protein Degradation Summit, October 25-28, 2022, in Boston. 

Researchers in academia, at either the graduate or postdoctoral level at the time of studies conducted and/or published, will be eligible for this award. Applicants must have demonstrated professional and scientific leadership in protein degradation and exhibited scientific curiosity and an established pattern of creative thinking and must not have a direct role in patient diagnosis and/or treatment. Only applicants who meet the full eligibility criteria will be considered.

Applications will be accepted today through August 1, 2022, at midnight Eastern Time. Full eligibility criteria and details on the application process can be found on Arvinas.com.

   
  9. Limited Submission Funding Opportunities
 

We ask that all MGH Investigators interested in applying for any limited submission award submit a Letter of Intent (see detailed instructions below) to the MGH Executive Committee on Research (ECOR) by the deadline indicated for each award to be considered to receive an institutional nomination. 

Process
Submit a one- to two-page Letter of Intent (LOI) to the MGH Executive Committee on Research (ECOR) via email to ecor@partners.org. In addition to your LOI, please include an NIH Biosketch. 

The letter of intent should include: 

  1. Name of the Principal Investigator with appropriate contact information 
  2. A descriptive title of the potential application 
  3. Brief description of the project 
  4. Brief description of why you specifically should be selected to receive institutional nomination for this award 

If there is more than one MGH investigator interested in applying for each limited submission award, the LOIs will be used to assess candidates and a review and selection process will take place. 

Current Limited Submission Funding Opportunities
Please click here for more information and for our internal deadlines. 

  • NIAMS Rheumatic Diseases Research Resource-based Centers (P30 – Clinical Trial Not Allowed) 

If there is a limited submission funding opportunity you do not see listed above or you have any additional questions, please let us know at ecor@mgh.harvard.edu

   
  10. Foundation Funding Opportunities
 

Please contact Corporate & Foundation Relations in the Office of Development at devcfr@mgh.harvard.edu if you wish to submit a proposal in response to any of these opportunities. Note that proposals are still routed through the standard Insight/Research Management process. 

Please be aware that any grant that brings in less than 20% in indirect costs (IDC) will need to be supplemented up to the 20 percent equivalent by existing investigator or departmental sundry funds. Resolution of this issue must occur prior to submitting a proposal. Training fellowships from foundations, public charity, and non-profit organizations are excluded from this minimum IDC requirement. 

Week of 06/24/22 

  • AGA-Pfizer Pilot Research Award in Non-Alcoholic Steatohepatitis, American Gastroenterological Association (AGA) Research Foundation NEW! $30,000. Application Deadline: August 23 
  • AGA Pilot Research Award, American Gastroenterological Association (AGA) Research Foundation. $30,000. Application Deadline: August 23 
  • AGA Pilot Research Awards in Digestive Disease Health Disparities, American Gastroenterological Association (AGA) Research Foundation. $30,000. Application Deadline: August 23 
  • Single Ventricle Research Fund (SVRF), Additional Ventures. $600,000. LOI Deadline: August 5 
  • Anne & Irving Brodsky (Quality of Life) Innovation Grant, Alzheimer's Foundation of America (AFA). $25,000. Application Deadline: September 16 
  • Birtman Grant, American Hearing Research Foundation (AHRF). $50,000. Application Deadline: August 15 
  • Community Sleep Health Grant, American Academy of Sleep Medicine (AASM) Foundation NEW! $20,000. LOI Deadline: Continuous 
  • Award for Research on Conditions Disproportionately Affecting Minorities, American Society of Gene and Cell Therapy. $50,000. Application Deadline: August 1 
  • Career Development Awards, American Society of Gene and Cell Therapy. $100,000. Application Deadline: August 1 
  • Damon Runyon Fellowship Award, Damon Runyon Cancer Research Foundation. $223,000. Application Deadline: August 15 
  • Mentored Research Award (MRA) Program, Hemostatis and Thrombosis Research Society (HTRS). $165,000. Preliminary Proposal Deadline: August 8 
  • Diversity Supplement, Lupus Research Alliance NEW! $30,000. Application Deadline: August 29 
  • Clinician Scientist Development Awards, National Multiple Sclerosis Society (NMSS). Unspecified Amount. Pre-Application Deadline: August 10 
  • Harry Weaver Neuroscience Scholar Awards, National Multiple Sclerosis Society (NMSS). Unspecified Amount. Pre-Application Deadline: August 10 
  • Postdoctoral Fellowships, National Multiple Sclerosis Society (NMSS). Unspecified Amount. Pre-Application Deadline: August 10 
  • Research Grants, National Multiple Sclerosis Society (NMSS). $600,000. Pre-Application Deadline: July 13 
  • Sylvia Lawry Physician Fellowship Program, National Multiple Sclerosis Society (NMSS). $195,000. Pre-Application Deadline: August 10 
  • Geriatric Microbiome Global Grants for Gut Health, Nature Research/Springer Nature. $100,000. Application Deadline: September 14 
  • Michael J. Davidson Structural Heart Fellowship Award, Thoracic Surgery Foundation (TSF). $50,000. Application Deadline: September 15 
  • Nina Starr Braunwald Research Award, Thoracic Surgery Foundation (TSF). $170,000. Application Deadline: September 15 
  • Nina Starr Braunwald Research Fellowship, Thoracic Surgery Foundation (TSF). $120,000. Application Deadline: September 15 
  • Research Award, Thoracic Surgery Foundation (TSF). $180,000. Application Deadline: September 15 
  • Resident Research Fellowship, Thoracic Surgery Foundation (TSF). $120,000. Application Deadline: September 15 
  • In Utero: Measurement and Modelling During Gestational Development, Wellcome Trust NEW! $50 million available. Abstract Deadline: June 30 
   
   
 
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NIH Update for Week Ending June 24, 2022

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Executive Committee On Research (ECOR) Massachusetts General Hospital
125 Nashua Street, Suite 822, Boston, MA 02114
ecor@mgh.harvard.edu