Research News - April 8, 2016

The ICJME (International Committee of Medical Journal Editors) is requesting feedback/comments on a new proposed requirement for investigators to share de-identified individual-subject data (IPD) from their clinical trials, no later than 6 months after publication.

Note: ICMJE has for several years required, as a condition of publication, that clinical trials be registered on CT.gov prior to the enrollment of the first subject.    This new proposal expands this requirement by requiring a detailed data sharing plan as part of the CT.gov registration.  The plan must include where the researchers will house the data and if not in a public repository, the mechanism by which they will provided others access to the data and the plan must be in submitted manuscript.

If the policy is adopted, clinical trials that begin to enroll participants 1 year after policy adoption must comply. 

ICMJE is asking for comments on the following 4 specific areas:

• Do you agree with the general requirement to share participant level data?
• Is 6 months after publication too soon? Too late? Just right?
• Do you agree with the requirement to include a detailed data sharing plan at the time of CT.gov registration (prior to enrollment of the first subject)?
• Do you agree that an alternate means of giving credit to the data generator who shares data must be developed?  

The attached link includes:

• A link to the proposal itself
• The ICMJE feedback form AND
• A link to comments that have already been posted.

https://forms.acponline.org/webform/comments-icmje%E2%80%99s-proposals-sharing-clinical-trial-data

The ORCD is sponsoring consultation meetings for faculty and research fellows to meet with Amy Robb, Assistant Director for Prospect Research and Funding Opportunities, Corporate & Foundation Relations, MGH Development Office, to set up personalized funding searches. Amy can meet with individuals or small groups who share funding goals. There are currently slots available in April 2016.

This consultation will help you:

• Set up search parameters designed to identify funding sources for your research program
• Receive a weekly report of updated search results
• Gain a greater understanding of how to use COS Pivot to conduct additional searches on your own

Please click here to read the latest news from the Patient-Centered Outcomes Research Institute.

Wednesday, April 27, 3:00 - 4:00 pm, MGH Main Campus, details provided upon registration

The Center for Faculty Development's Office for Research Career Development presents a seminar for HMS faculty and trainees.

Research Integrity – It’s a Matter of Trust
This Responsible Conduct of Research (RCR) seminar will discuss:

• Public perceptions of scientific research
• Integrity in collaborations and publications
• Integrity in data management
• Perspectives of an HMS policymaker and a senior faculty member

Speakers: Gretchen Brodnicki, JD, Dean for Faculty and Research Integrity, HMS
Dennis Brown, PhD, Professor of Medicine, Director, Office for Research Career Development

Please click here to register by Fri, Apr 22.

Monday, April 11, 2016, 4:00- 5:00 pm, CNY 149, 7th Floor, Isselbacher Auditorium

“Therapeutic Targeting of VISTA in oncology and autoimmunity”
Randolph J. Noelle, PhD
Professor, Department of Microbiology and Immunology
Geisel School of Medicine, Dartmouth College

Registration at Lobby Security Desk may be required

Shuttle bus leaves MGH Main Campus (Blossom St.) every 15 minutes

Refreshments available prior to start of talk

Contact person: vtheodoracopoulos@partners.org

Tuesday, April 12, 4:00 - 5:00 PM, CNY 149, 2.204

Role of metabolism in supporting tumor growth
Matthew Vander Heiden, MD, PhD
Associate Professor of Biology
Koch Institute for Integrative Cancer Research at MIT

Friday, April 15, 2016, 11:30 - 2:00 pm, CNY campus

Join the MGPA for a two-part event including an MGPA Academic Career Series panel discussion followed by a vendor fair, highlighting equipment and supplies for wet labs. 

Part I - Panel Discussion
11:30 to 12:30 pm
"Tips for the NIH K99 Pathway to Independence Grant" (for postdocs) 
Panelists: Matt Dubach, PhD, Hyungsoon Im, PhD, Imran Rizvi, PhD, and Bryan Spring, PhD

This panel discussion will feature MGH K99 awardees who will offer tips and advice on putting together your best application for this competitive award. From the NIH web site: This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers. The K99/R00 grant is open to non-US citizens/permanent residents.

Part II - Vendor Fair
12:30 to 2:00 pm
Speak to vendors about the newest equipment and supplies that will advance your research. 
   (for faculty and postdocs)

Please click here to register by Wed, Apr 13.

Wednesday, June 8, 2016; 1:00pm – 5:00pm, O’Keeffe Auditorium, Blake 1 

Abstract Submission Deadline:  May 9th at 5pm EDT

The Center for Skeletal Research (CSR), based in the Endocrine Unit at MGH, and funded by a NIAMS P30 grant,  is happy to announce its second annual Research Symposium. The goal is to bring together the Boston bone research community for an exciting afternoon of scientific exchange. This year we will again feature talks by two talented leaders of the field from outside the Center. New this year is a special meeting with Drs. Joan McGowan and Faye Chen for young investigators. We will also be expanding the poster session and will again offer prizes. Posters will be displayed in the Bulfinch Patio Tent. We ask that you register for the meeting so we can get a good sense of the number of attendees in advance and because seating is limited. 

Preliminary applications are now being accepted by the Executive Committee on Research (ECOR) for the
Pew Scholars Program in the Biomedical Sciences Awards

What are they?
Pew Scholars Program in the Biomedical Sciences Awards
The Pew Scholars Program in the Biomedical Sciences provides funding to young investigators of outstanding promise in science relevant to the advancement of human health. The program makes grants to selected academic institutions to support the independent research of outstanding individuals who are in their first few years of their appointment at the Assistant Professor level.

MGH is eligible to nominate one candidate.

When is the deadline?  
MGH internal preliminary applications: Tuesday, May 17, 2016 – 5:00 PM

How do I learn more and apply?
Pew Scholars Program in the Biomedical Sciences Awards - Click here

Please contact Corporate & Foundation Relations in the Office of Development at devcfr@mgh.harvard.edu if you wish to submit a proposal in response to any of these funding opportunities.  Note that proposals are still routed through the standard InfoEd/Research Management process.

• Dr. William E. Paul Distinguished Innovator Awards in Lupus and Autoimmunity, Lupus Research Institute (LRI)
• Novel Research Grant Program - New Research Grants for Novel Approaches to Lupus, Lupus Research Institute (LRI)

Please click here for further details on these funding opportunities.

We ask that all MGH Investigators interested in applying for any limited submission award submit a Letter of Intent (see detailed instructions below) to the MGH Executive Committee on Research (ECOR) by the deadline indicated for each award to be considered to receive an institutional nomination.

Process
Submit a one- to two-page Letter of Intent (LOI) to the MGH Executive Committee on Research (ECOR) via email to ecor@partners.org.  In addition to your LOI, please include an NIH Biosketch.

The letter of intent should include:

• Name of the Principal Investigator with appropriate contact information
• A descriptive title of the potential application
• Brief description of the project
• Brief description of why you specifically should be selected to receive institutional nomination for this award

In the event that there is more than one MGH investigators interested in applying for each limited submission award, the LOIs will be used to assess candidates and a review and selection process will take place.

Current Limited Submission Funding Opportunities
Please click here for more information and for our internal deadlines.

• Consortium for Food Allergy Research: Leadership Center (UM2)
• Consortium for Food Allergy Research: Clinical Research Units (UM1)

If there is a limited submission funding opportunity you do not see listed above or you have any additional questions, please contact Erin McGivney at 617-643-6471.

For the latest National Institutes of Health notices, requests for applications, and program announcements, follow this link: http://grants.nih.gov/grants/guide/WeeklyIndex.cfm

MGH ECOR Formulaic Bridge Funding Support
Application Deadline: May 7; 7th day of each month

KL2 Catalyst Medical Research Investigator Training (CMeRIT) Award
Application Deadline: April 14

Heart Rhythm Society Atrial Fibrillation (AFib) Quality Improvement Innovation Grants
Application Deadline: April 18

Boston Biomedical Innovation Center (B-BIC) Accepting PILOT & DRIVE Grant Pre-Proposals

Responsible Conduct of ‘Omics’ Research – May 24

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