Research News - September 22, 2017

If you would like to submit a question for Dr. Slavin to address at the October 2 Research Council meeting, where he will be conducting his “Annual Conversation with the Research Community”, email your question to us at ecor@mgh.harvard.edu.

Annual ECOR Elections for Representatives from the MGH Research Community
Nominate Yourself or a Colleague!

Nominations Deadline:
Friday, September 29

- TWO OPENINGS -
One Associate Professor
One Professor

For information about ECOR & ECOR Reps responsibilities go to: http://ecor.mgh.harvard.edu/about/elections

Nomination form: https://ecor.mgh.harvard.edu/elections/NominationForm.aspx

Questions? ECOR@mgh.harvard.edu

The MGH Youth Programs team is seeking volunteers to mentor Boston middle school students through their science fair projects. Mentors meet with students at MGH or the Charlestown Navy Yard on two Friday mornings each month, October through January. No particular expertise in mentoring or science fair projects needed! The MGH Youth Programs team provides ongoing mentor training and support. For more information, please contact Caroline Hone at chone@partners.org or 617-643-6287.

On September 25, 2017, Apple will release their next Operating System (OS) for Mac laptops & desktops, macOS High Sierra. At this time, we recommend you do not upgrade your Mac as this upgrade may impact your ability to use enterprise services… view the PEAS Service Alert.

As promoted during Research Council, we have selected our raffle winner from the Research Resource Room drawing on September 5th.  Jim Winter from the IACUC department was our lucky winner of a $50 MGH Café gift card!  Congratulations, Jim!

We hope to see you all at the next Research Resource Room, following Research Council on Monday, October 2.

“Wound healing and regeneration in the skin”
Mayumi Ito, PhD
Associate Professor, The Ronald O. Perelman Department of Dermatology
Department of  Cell Biology
New York University School of Medcine

Monday, September 25, 2017, 4pm to 5pm
MGH East Building 149
Isselbacher Auditorium 7th Floor
Charlestown, MA
Shuttle bus leaves MGH Main Campus (Blossom Street) every 15 minutes

Thursday, September 28 @ 3:00pm, 149 CNY / 2.204
Molecular Thermo-Biology in Physiology and Disease
Shingo Kajimura, PhD
Associate Professor
University of California, San Francisco

Tuesday, October 3 @ 4:00pm, 149CNY / 2.204
E. Dale Abel, MD, PhD
Metabolism and Heart Failure
Director, Division of Endocrinology and Metabolism
Professor of Internal Medicine - Endocrinology and Metabolism
Professor of Biochemistry
University of Iowa

Join ORCD and PDD staff for an interactive workshop to learn more about popular tools for career exploration and professional development including the Academic Career Readiness Assessment, the Individual Development Plan and the Annual Career Planning Form.
It's not too early to start thinking about your next steps. Learn how to use these tools to maximize your options, develop your skills, identify transferable skills and prepare for your next move with confidence.
Two sessions will be offered. Please register for the session most convenient for you.

Main Campus Session:
Wednesday, October 11, 2017
Time: 12:00-1:00pm
Main Campus

CNY Campus Session:
Tuesday, October 24, 2017
Time: 12:00-1:00pm
CNY Campus

You may register for the Main Campus Session here and the CNY Campus Session here. Email pdd@partners.org with questions.

Thursday, September 28, 2017@ 12:00 PM, CNY149, 7th Floor, Isselbacher Auditorium

Title: “Lessons from the analysis of the immune response to P. falciparum”
Speaker: Antonio Lanzavecchia, PhD. Institute for Research in Biomedicine (IRB), Switzerland
Date & Time: Thursday, September 28, 2017@ 12:00 PM
Location:
Isselbacher Auditorium

MGH East, Building 149, 7th Floor

Charlestown Navy Yard

(shuttle bus leaves MGH and North Station every 15 minutes)
Will be broadcasted MGH Bulfinch 165
Contact Person – Fiona Chen (617/726-1527)
http://www.massgeneral.org/ciid/ourseminars/seminarseries.aspx

Thursday, October 5

The Division of Clinical Research invites you to join us for our 15th annual MGH Clinical Research Day on Thursday, October 5th. The day starts at 8:00am in the O'Keeffe Auditorium and features:

8am – 9am– Keynote Address
Genomic and Precision Medicine: Its time has arrived
Daniel Rader, M.D., Chair, Department of Genetics, Perelman School of Medicine University of Pennsylvania and Children’s Hospital of Philadelphia

9am – 11am Poster Session I – Individual Submissions
View posters by researchers from across the institution in the Individual Submissions category.

11am – 12pm Panel Discussion
How is Personalized Medicine Impacting Care Now and Shaping Our Future?

12pm – 1pm Poster Session II – Team Submissions
View posters by researchers from across the institution in the Team Submissions category.

The keynote address and panel discussion will be held in the O'Keeffe Auditorium and the poster session will be held under the Bulfinch tents.

Please click here for the MGH Clinical Research Day 2017 Event Schedule.

Monday, October 16, 2017, Time: 3:00 to 4:00 pm, MGH Main Campus, details provided upon registration.

The Office for Research Career Development presents a seminar for research faculty and fellows.

Do you have questions about how to set expectations in your lab with regard to authorship?
Are you a trainee wondering how to discuss authorship with your PI and colleagues?
This seminar will provide answers and a discussion forum for topics related to manuscript authorship, including:

• Formal guidelines
• Gray areas in authorship decisions
• Evolution of author groups
• Dispute resolution

Facilitator: Andrew T. Chan, MD, MPH, associate professor of medicine, HMS; program director, gastroenterology training program, MGH; chief, clinical and translational epidemiology unit, MGH; and the Stuart and Suzanne Steel MGH research scholar

Please click here to register by Wed, Oct 11.

This seminar counts as one of the four required lectures in part III of Partners RCR training. All are welcome, but space is limited and registration preference will be given to those with RCR training requirements.

Tuesday, October 17, 1:00pm – 3:00pm, Simches Room 3.120

Speaker: John Putzke, Ph.D., M.S.P.H.
Bio: http://www.sciencetrax.com/wp-content/uploads/Putzke_CurriculumVitae.pdf

Upon conclusion of this program, participants should be able to:
·        Identify common factors associated with subject dropout and missing data
·        Recognize the challenges that delay data analysis and publication of results
·        Appraise software strategies for engaging subjects and finding results quicker

Summary
The essence of clinical research is the capture of data from subjects.  Historically, subjects have experienced little more than the burden of appointments and completing forms.  Moreover, existing database systems involve a complicated, time-consuming process to transform data into information.  
Advances in information technology and devices offer considerable promise with regard to overcoming these common challenges.  Innovative software strategies to integrate device data, gamification, and delivery of personally relevant information and incentives are exciting new ways to engage and strengthen the commitment of subjects.  Building database systems around the dissemination phase (e.g., data analysis, publication of results) will dramatically help clinical investigators answer questions quicker.  Examples will be demonstrated using StudyTRAX, an electronic data capture (EDC) system.

To learn more about visit:
StudyTRAX:    http://rc.partners.org/edcstrax
                        www.studytrax.com

Registration is required. Please contact Cassidy Peters with any questions.

Wednesday, October 18, 2017, 9:00 – 12:30pm, Garrod Mendel Conference Room

This orientation program will provide Fellows who are completing their clinical year and entering their research years at MGH with an overview of the process of clinical and translational research at MGH. In this course, participants will receive an overview of clinical research at MGH, review the overall architecture of clinical research, and will be introduced to key resources available to clinical/translational investigators at MGH.
This course will be limited to Fellows who are completing their clinical year and entering their research years at MGH.
Please register here: Clinical Research Fellows Orientation Please contact Tiereny Morrison-Rohlfs with any questions.

Applications are now being accepted by the Executive Committee on Research (ECOR) for the MGH Research Scholars Program

What is it?
The Massachusetts General Hospital Research Scholars Program was established with the aim of supporting MGH research faculty who are pursuing either fundamental (basic) or clinical research at the level of Assistant, Associate or Full Professor.  The intent of these awards is to support the careers of outstanding MGH investigators doing cutting-edge research that is highly innovative and expected to result in fundamental scientific discoveries and/or clinical applications.  This year, we are asking applicants to choose one of three categories based on the research proposed in the application: Clinical research, Fundamental research, or Population and healthcare research.

How much is each award?
These awards are for $500,000 over 5 years; and will be funded at $100,000 per year, including 15% indirect costs.

When is the deadline?
Thursday, October 12, 2017 – 5:00 PM

How do I learn more and apply?

• Click here to read more and apply online.
• Click here to see a list of past recipients.
• Visit the ECOR website for other funding opportunities.

Applications are now being accepted by the Executive Committee on Research (ECOR) for the Tosteson and Fund for Medical Discovery (FMD) Postdoctoral Fellowship Awards!

What is it?
The Tosteson & FMD Awards are intended to support junior investigators (MD and PhD Research Fellows/Clinical Research Fellows) at Massachusetts General Hospital pursuing either fundamental (basic) or clinical research.  

The ECOR Subcommittee on Review of Research Proposals (SRRP) reviews the applications and selects the awardees. The top three applicants will receive Tosteson Awards - named for the longtime Dean of the Harvard Faculty of Medicine - and the remaining awardees receive FMD awards.

How much is each award?
The awards will include a stipend of $47,500 plus applicable fringe benefits and 15% indirect costs.

When is the deadline?
Monday, October 2, 2017 - 5:00 PM

How do I learn more and apply?

• Click here to read more and apply online.
• Visit the Tosteson and Fund for Medical Discovery page on the ECOR website here.

Applications are now being accepted by the Executive Committee on Research (ECOR) for the MGH Howard M. Goodman Fellowship
What is it?
This is an endowed fellowship established by the MGH Department of Molecular Biology in honor of the founding Chief of the Department, Dr. Howard M. Goodman. The award is intended to further the careers of outstanding independent young scientists, who would normally hold the position of Assistant Professor, and have demonstrated the potential to rise to a leadership position in their chosen field. Applicants who hold a full-time appointment in any MGH Department and are primarily engaged in research, are eligible to apply.

How much is the award?
The award is for two years at $150,000, plus 15% indirect costs, per year and is effective April 1, 2018.  

When is the deadline?
Wednesday, October 25, 2017 – 5:00 PM

How do I learn more and apply?

• Click here to read more and apply online.
• Click here to see a list of past recipients.
• Visit the ECOR website for other funding opportunities.

Applications are now being accepted by the Executive Committee on Research (ECOR) for the
Claflin Distinguished Scholar Awards!

What are the Claflin Awards?
Although women scientists are recruited to Massachusetts General Hospital (MGH) programs, their advancement to senior faculty positions is still far less frequent than that of their male counterparts.  In 1993, The Women in Academic Medicine Committee, originally chaired by Mrs. R. Morton Claflin, Honorary Trustee, was established to facilitate the academic careers of women in science at MGH.  Recognizing that a significant obstacle to career advancement is the difficulty of maintaining research productivity during the child-rearing years, this Committee, with the sponsorship of the Executive Committee on Research (ECOR), established the Claflin Distinguished Scholar Awards.  It is intended that this funding will increase opportunities for women to advance to senior positions in academic medicine.

How much is each award?
These are two year awards for $50,000 per year in direct costs, plus 15% for indirect costs.

When is the deadline?
Wednesday, October 11, 2017 - 5:00 PM

How do I learn more and apply?
Click here to read more and apply online!

The Boston Area Diabetes Endocrinology Research Center
is now accepting Pilot and Feasibility Research Grant Award Applications
For studies of Diabetes Mellitus and Its Complications

The Boston Area Diabetes Endocrinology Research Center is funded by the National Institute of Diabetes and Digestive Diseases (NIDDK) to support research in Diabetes and its complications.  Research grants up to $30,000 will be awarded for meritorious proposals from candidates whose eligibility is defined by one or more of the following three criteria:

1. Junior faculty without past or current NIH support to conduct Diabetes research.
   Not eligible if you have any support that is mandatory 100% effort where you cannot accept any federal funding.
2. Established non-Diabetes researchers who have an innovative idea relevant to Diabetes.
3. Established Diabetes investigators who have an innovative idea/approach relevant to Diabetes that represents a distinct departure from their established line of investigation.
4. Co-PI’s are not allowed, and if you are not accepting salary and or less than 5%, please mention if there is cost sharing.

It is anticipated that up to four meritorious applications will be funded.                                  

Letters of Intent, Biosketch, Other support and Abstract due Monday, September 18, 2017
If proposal accepted, Applications due by Monday, October 23, 2017

                If you qualify based on one of the three criteria listed above, please email a letter of intent in MS Word that includes your name, degree, title and email address and a brief description of your research.  In addition to the LOI email, please include an abstract with the title of your project (NIH form page) of your research, a biosketch and OS page.    If your proposed research is deemed compatible with the goals of the BADERC, instructions for the preparation of a five-page application for a Pilot and Feasibility Research Grant Award will be forwarded to you.  The deadline for the Grant application will be October 23, 2017.  Funding will be effective April 1, 2018.

Please send Letters of Intent and abstract page with the title of your project in word
via (email) to Prendable@molbio.mgh.harvard.edu

We ask that all MGH Investigators interested in applying for any limited submission award submit a Letter of Intent (see detailed instructions below) to the MGH Executive Committee on Research (ECOR) by the deadline indicated for each award to be considered to receive an institutional nomination.

Process
Submit a one- to two-page Letter of Intent (LOI) to the MGH Executive Committee on Research (ECOR) via email to ecor@partners.org.  In addition to your LOI, please include an NIH Biosketch.

The letter of intent should include:

• Name of the Principal Investigator with appropriate contact information
• A descriptive title of the potential application
• Brief description of the project
• Brief description of why you specifically should be selected to receive institutional nomination for this award

If there is more than one MGH investigator interested in applying for each limited submission award, the LOIs will be used to assess candidates and a review and selection process will take place.

Current Limited Submission Funding Opportunities
Please click here for more information and for our internal deadlines.

• George M. O'Brien Kidney Research Core Centers (P30)
• Stimulating Access to Research in Residency (StARR) (R38) – NEW!
• Population Dynamics Centers Research Infrastructure Program FY 2018 (P2C)
• Dr. Ernest J. Ring Academic Development Grant (SIR Foundation) – NEW!

If there is a limited submission funding opportunity you do not see listed below or you have any additional questions, please let us know at ecor@mgh.harvard.edu.

Please note that any grant that brings in less than 15% in indirect costs (IDC) will need to be supplemented up to the 15% equivalent by existing investigator or departmental sundry funds. Resolution of this issue must occur prior to submission of the award.

Please contact Corporate & Foundation Relations in the Office of Development at devcfr@mgh.harvard.edu if you wish to submit a proposal in response to any of these funding opportunities.  Note that proposals are still routed through the standard InfoEd/Research Management process.

Week of 9/22/17

• Heart to Heart Grant, Alpha Phi Foundation
• Academic Scholarship, American Association Of Plastic Surgeons (AAPS)
• Franklin H. Martin, M.D., FACS, Faculty Research Fellowship of the American College of Surgeons, American College of Surgeons (ACS)
• Collaborative Sciences Award, American Heart Association (AHA)
• National Endowment for Plastic Surgery Grant, American Society of Plastic Surgeons (ASPS)/Plastic Surgery Foundation (PSF)
• AST TIRN Fellowship Research Grants, American Society of Transplantation (AST)
• Innovative Research Call, DEBRA International
• Annual DeGregorio Foundation Award for Cancers of the Esophagus and Stomach, DeGregorio Family Foundation for Stomach and Esophageal Cancer Research and Education
• Scientific Scholar Award, Marsha Rivkin Center for Ovarian Cancer Research 
• NPKUA Post-Doctoral Fellowship, National PKU Alliance (NPKUA)
• Junior Faculty Career Development Award, National Palliative Care Research Center (NPCRC)
• Pilot and Exploratory Project Support Grant, National Palliative Care Research Center (NPCRC)
• Research Grants Program, Partnership for Clean Competition (PCC)
• Independent Grants for Learning & Change (IGL&C):  Improving Patient Care in Inflammatory Bowel Disease (IBD) through Shared Decision-Making, Pfizer, Inc.
• Building Trust and Mutual Respect to Improve Health Care, Robert Wood Johnson Foundation (RWJF)  
• Gene-Targeting Strategies for Neurofibromatosis Type 1, The Gilbert Family Foundation (GFF)
• TSA Research Grant and Fellowship Program, Tourette Association of America

For the latest National Institutes of Health notices, requests for applications, and program announcements, follow this link: http://grants.nih.gov/grants/guide/WeeklyIndex.cfm

Partners Innovation Discovery Grant Program - Artificial Intelligence, Data Science, Cognitive Computation, and Machine Learning
Application Deadline: September 25

Tosteson & Fund for Medical Discovery (FMD) Postdoctoral Fellowship Awards
Application Deadline: October 2

MGH ECOR Formulaic Bridge Funding Support
Application Deadline: October 7, 2017; 7th day of each month

MGH Claflin Distinguished Scholar Awards
Application Deadline: October 11

MGH Research Scholars Program
Application Deadline: October 12

The Football Players Health Study
Application Deadline: October 13

Pfizer Centers for Therapeutic Innovation Fall 2017
Application Deadline: October 13

HMS Foundation Funds
Application Deadline: October 16

Howard M. Goodman Fellowship 2018
Application Deadline: October 25

Bullock Postdoctoral Fellowship
Application Deadline: November 1, 2017

Boston Biomedical Innovation Center (B-BIC) Accepting PILOT & DRIVE Grant Pre-Proposals

Technical Training Session on ClinicalTrials.gov Registration and Results Reporting – October 10
Clinical Research Billing from Study Start to Completion – October 12

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