Research News - November 4, 2016

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MGH Research News
Executive Committee on RESEARCH fostering Innovation at MGH RESEARCH MANAGEMENT. Mainstay ofMGH Innovation
 
November 4, 2016
ANNOUNCEMENTS
 

1. Clinical Trials Office (CTO) Help Line
2. Exhibit Policy
3. Upgrade your Apple iOS devices

 

EVENTS
 

1. MGH Research Council
2. Cardiovascular Research Seminar
3. REGISTER NOW! Elevate Your Science: A Research and Presentation Skills Symposium
4. Identifying External Funding Opportunities with COS Pivot
5. LGBTQ in the Labs: Postdoc and PhD Mixer
6. HMS Faculty Seminar - “Meet and Greet” Faculty Networking Reception with Dr. Connie Cepko
7. IRB Roundtable: Consent Form Writing
8. QI Roundtable: Informed Consent Process

FUNDING OPPORTUNITIES
 

1. MGH ECOR Deliberative Interim Support Funding
2. Call for Nominations: Mallinckrodt Scholar Program
3. Exciting Industry Fellowship Opportunities
4. MIT and Philips are pleased to announce a new Research Award for Clinicians
5. Merck KGaA Darmstadt Germany Biopharma Innovation Cup 2017
6. Limited Submission Funding Opportunities
7. Private Funding Opportunities
8. NIH Update for Week Ending November 4, 2016

In Case You Missed It
 
Reminders of recently posted funding opportunities, deadlines and events
 
ANNOUNCEMENTS
 
1. Clinical Trials Office (CTO) Help Line

The Clinical Trials Office (CTO) Help Line has changed since our move to Assembly Row.  Please note our new number is 857-282-5787.

The email Help Line address remains the same at  CTOmailbox@partners.org.  The PHS research community may use this for information, assistance and answers to questions related to industry-sponsored clinical research contract and budget negotiation and approval, fund activation, Medicare Coverage Analysis and Medicare device petition issues.   

Experienced CTO staff will respond to routine calls and emails within one business day.    Urgent matters will be addressed immediately.
 
2. Exhibit Policy

Many educational programs, both accredited and non-accredited, sell exhibit space to offset the cost of an educational activity. This sale of exhibit space provides valuable resources to support Partners educational activities, fulfilling one of the core areas of our charitable mission, and in most situations is welcomed and encouraged. 

However, senior hospital and Partners leadership has recently reviewed one type of situation where the sale of such exhibit space as part of a Partners educational activity has been determined to be problematic. Hospital and Partners leadership decided that the sale of exhibit space at an educational activity that takes place directly on the hospital premises is not appropriate. The primary concern is that exhibit space inherently involves a type of promotional activity for the company involved. Hospital and Partners leadership does not think it is appropriate for companies to showcase themselves and their products in areas where patients and members of the public are present, as it may appear to patients that the hospital is endorsing or supporting the particular company or companies exhibiting. There are other policy and legal concerns with these transactions, as well. In addition to exhibit booths, other forms of “promotional opportunities” that are sometimes offered to companies in connection with Partners educational activities may raise the same concerns – those will be looked at on a case by case basis. If your department wishes to pursue this type of promotional opportunity, or if you have general questions about this topic, please contact Erin Stewart in the Partners Office for Interactions (OII) at ecstewart@partners.org.

Many Partners educational activities do not take place on hospital premises and are held at off-site conference facilities. The sale of exhibit space and other forms of promotional opportunities are still allowable within the boundaries of other pre-existing policies and ACCME requirements on this topic. 

This policy change is effective immediately, but if you have concerns, please contact Erin Stewart in OII and she will share any concerns with appropriate senior leadership. 

 
3. Upgrade your Apple iOS devices

On 10/24/2016 Apple released an important patch (10.1, followed by 10.1.1) for their mobile operating system (iOS). This update fixed multiple vulnerabilities that might lead to remotely acquiring control of your device… click for more.

 
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EVENTS
 
1. MGH Research Council

Monday, November 7, 2016, 12:00 - 1:00 PM, Simches Auditorium (3.110)
Broadcast to Isselbacher Auditorium (CNY-149, 7th Floor)

ECOR Elections - Come Meet the Candidates!
Come meet the six candidates running in the 2016 ECOR elections.
This is a great opportunity to help you decide how to vote!

MGH Research Cores
Dennis Brown, PhD, Director, Office for Research Career Development
Susan Slaugenhaupt, PhD, Scientific Director, Research Institute

Partners Core Initiatives
Narayanaswamy Ramesh, Sr. Manager, Partners Research Cores

All MGH Researchers welcome!

 
2. Cardiovascular Research Seminar

Tuesday, November 8, 4:00 - 5:00 pm, CNY 149, Room 2.204

EGLN1 Inhibition is Sufficient for Remote Cardioprotection
Benjamin A. Olenchock, MD, PhD
Brigham and Women's Hospital

 
3. REGISTER NOW! Elevate Your Science: A Research and Presentation Skills Symposium

Wednesday, November 9, 4:30 - 6:30 pm (followed by a network reception), MGH Main Campus,details provided with registration

The Mass General Post-doc Association (MGPA) presents a session for MGH research faculty and trainees.

Want to learn how to give a great talk to an academic or industry audience? Come learn presentation tips from experts and watch as your fellow postdocs present their research. This symposium will help you craft the perfect science talk to advance your career!


Elevate Your Science: A Research and Presentation Skills Symposium
Featured panelists include:

  • Adam Castoreno, PhD, Senior Scientist, Alnylam Pharmaceuticals
  • Alessio Fasano, MD, Director, MGH Mucosal and Immunology and Biology Research Center; Division Chief,  MGHfC Pediatric Gastroenterology and Nutrition

Space is limited, please click here to register. Contact mgpa@partners.org if you have any questions.

 
4. Identifying External Funding Opportunities with COS Pivot

Thursday, November 10, 12:00 - 1:00 pm, Garrod Mendel Conference Room

Are you interested in finding research or programmatic funding?  Pivot contains open calls for proposals and letters of intent for grants, awards, prizes, and fellowships, as well as support for travel, conferences, and equipment acquisition.  Federal, philanthropic, commercial, and international funding sponsors are included.  Pivot allows researchers to easily limit results by criteria including citizenship or residency, geographic location, or professional rank.

Come to this seminar to learn how you can:

  • Access Pivot and save searches to receive automated alerts regarding relevant funding opportunities
  • Diversify your funding portfolio by employing strategies to match your research with sponsors’ unique funding priorities

Please feel free to contact Joseph Connolly Jdconnolly@partners.org with any other questions regarding the course.

 
5. LGBTQ in the Labs: Postdoc and PhD Mixer

Thursday, November 10, 4:00 - 6:00 pm, NRB 1031, (77 Avenue Louis Pasteur, Boston, MA)

Please join other postdocs, PhD students, faculty, trainees and staff for a short talk with Sean Whelan, PhD about his life and career and then stay for the mixer.

RSVP here: https://www.surveymonkey.com/r/LGBTQintheLabs

 
6. HMS Faculty Seminar - “Meet and Greet” Faculty Networking Reception with Dr. Connie Cepko

Tuesday, November 15, 2016, 4:30 - 6:00 pm, Location provided upon registration

The Center for Faculty Development’s Office for Women’s Careers presents a seminar for MGH faculty with HMS academic appointments.

The OWC’s “Meet and Greet” networking series provides an opportunity for faculty to hear from a senior MGH faculty member about her career path, and is also a great way to meet colleagues in a relaxed setting. Connie Cepko, PhD, will join us as the guest speaker at this event. Join us to meet Dr. Cepko, hear about her career path and network with your MGH colleagues.

“Meet and Greet” Faculty Networking Reception with Dr. Connie Cepko
Speaker: Constance Cepko, PhD, Bullard Professor of Genetics and Neuroscience,
Professor of Ophthalmology, HMS, Howard Hughes Medical Institute Investigator

Please click here to register by Wed, Nov 9.

 
7. IRB Roundtable: Consent Form Writing

Thursday, December 1, 12:00 - 1:00pm, Simches Building, 2nd Floor, Garrod/Mendel Conference Room

Speaker: Amy Ben-Arieh, Senior Human Research Specialist/Administrative Chair, PHRO
Did you know that most of your research subjects are reading at the 8th-grade level or lower? Learn how to write the simplest, clearest consent forms, so that every one of your subjects can be fully informed. This workshop will teach you specific skills for writing easy-to-understand documents. The learning objectives of this session are for participants to understand the elements of consent, acquire plain language tips for editing research consent forms, and identify which Partners consent form template is appropriate for your protocol.

This session is limited to 25 participants to facilitate interaction.
Registration is required. Please contact Joseph Connolly with any questions.

 
8. QI Roundtable: Informed Consent Process

Thursday, December 15, 12:00 - 1:00pm, Simches Building, 2nd Floor, Garrod/Mendel Conference Room

Speaker: Charlene Malarick, RN, BSN, CCRC, Partners Human Research Quality Improvement Program

Informed consent: it’s more than just a document. Do you know the ethical considerations that factor into obtaining truly informed consent? If your study involves vulnerable populations, such as children, are you knowledgeable of the special protections afforded to them, and the Partner’s policies governing their consent? In this session, Charlene Malarick, RN, BSN, CCRC of the Partners Quality Improvement Program will discuss these issues and how to fulfill the Partner’s policies for documenting the informed consent process. She will describe the informed consent process, review vulnerable populations, the special protections afforded to them, and how these apply to the informed consent process, and discuss how to effectively comply with the Partners policies for documenting informed consent.

This session is limited to 25 participants to facilitate interaction.

Registration is required. Please contact Joseph Connolly with any questions.

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FUNDING OPPORTUNITIES
 
1. MGH ECOR Deliberative Interim Support Funding

The Executive Committee on Research (ECOR) is accepting applications for the December 1st deadline for the Deliberative Interim Support Funding.  December is the 1st of three standing deadlines for these awards in Fiscal Year 2017.  The next deadline will be April 1, 2017.  

What are they?
This is open to Principal Investigators during a lapse or delay in their research funding from the NIH or another Federal agency (e.g., the National Science Foundation, the Department of Defense).  Investigators must have applied for independent, long-term support (R01, R21, U01 and P01).  The Deliberative Interim Support process is open to:

  1. Investigators whose grants were not scored or whose scores were not translated into a percentile ranking.
  2. Investigators whose grants received scores >20th percentile.
  3. Investigators who have already received Formulaic Bridge Funding or Deliberative Interim Support on their A0 grant application and are now requesting support for their A1 or A0 resubmission.  Investigators in this category must apply through the Deliberative Interim Support process for their A1 and A0 resubmission regardless of the score they received on their resubmitted grant.

When is the deadline?
Thursday, December 1, 2016 - 5:00 PM

How do I learn more and apply?
Deliberative Interim Support Funding - Click here

 
2. Call for Nominations: Mallinckrodt Scholar Program

Harvard Medical School (including its affiliated health care institutions) has been invited to nominate up to two candidates for the 2017 Mallinckrodt Scholar Program.  This program, established by the Trustees of the Edward Mallinckrodt, Jr. Foundation provides support for early stage investigators engaged in biomedical research that has the potential to significantly advance the understanding, diagnosis, or treatment of disease. The Scholar Award provides $100,000 annually for four years.

Eligible candidates must:

  • Hold M.D. and/or Ph.D. degrees.
  • Be within five to eight years of their appointment to Assistant Professor January 15, 2017 (Associate professors may be eligible).
  • Have support to move their project forward to the point where other independent funding can be obtained. 

More information on the Mallinckrodt Scholar Program can be found at:
https://hms.harvard.edu/departments/office-academic-and-clinical-affairs/hms-foundation-funds/award-listing

To apply, a PDF that includes the following materials should be sent to Clare Lamont, Office of the HMS Dean for Academic and Clinical Affairs, 617-432-7463, clare_lamont@hms.harvard.edu

Required materials – Please send as a single PDF:

  • Proposal (up to five pages).  A detailed description of the project for the scientific members of the Board.  The five-page limit includes data and figures, etc.  References are not included in the five-page limit.
  • Project summary for the layperson (up to two pages).   Critical for non-scientist members of the Board.
  • Letter of recommendation.   Written by a senior faculty member or members who can represent the support of the institution and who are acquainted with the qualifications of the applicant and the potential impact of their work.
  • NIH Biosketch. (up to five pages).
  • Support.  Provide an adequate budget with a breakdown showing how the funds will be used.  It is important to justify how the funds to be received will be used to advance the proposed project in a way that cannot be done with existing funds.  In addition, the proposal must detail the levels of support of any grants already available or pending.  Candidates may have an R01, however, the proposed project will be less competitive if it already has significant funding.  Salary is allowed. 

Applications are due November 21, 2016 by 5:00PM

 
3. Exciting Industry Fellowship Opportunities

The Innovation Fellows Program is a new initiative that seeks to increase collaboration between the Partners HealthCare community and industry.

The program provides a two-way training opportunity where personnel are exchanged between the PHS core hospitals—Brigham and Women’s Hospital, Massachusetts General Hospital and McLean Hospital—and participating biopharmaceutical companies, investment funds and other commercial entities.
The program offers on-site experience within a company for postdoctoral fellows and junior faculty that can enhance the skills of the participants and train our investigators to better understand our industry partners.

The skills participants may acquire include clinical trial design, cutting-edge research techniques, project management, data analysis, drug development, protocol review, reimbursement considerations and regulatory interaction, among others.

Benefits:

  • Develop capabilities and skills across the R&D pipeline and commercialization process
  • Create and grow new industry partnerships and collaborations
  • Gain exposure to alternative career paths and/or new opportunities for career acceleration

Qualifications:

  • MD, PhD, or a joint degree
  • Clinical fellows must have completed their residency
  • Research fellows must have two years of postdoctoral training
  • Faculty

How to Apply:
For more information and to express your interest, visit the Partners HealthCare Innovation website.
Please respond by November 27.

 
4. MIT and Philips are pleased to announce a new Research Award for Clinicians
In May 2015 MIT and Philips Research North America entered into a 5-year $25 million research agreement to provide funding to build breakthrough collaborative research projects involving investigators from both institutions. In establishing this collaborative agreement, we recognize that deep clinical insight will be an essential element to the development of breakthrough healthcare technologies.
 
With this award we are establishing an environment for selected clinicians to pursue novel healthcare research together with MIT and Philips clinicians, scientist and engineers with whom they will collaborate on the translation of great ideas to solutions that have an impact on healthcare.
 
This award program is aimed at young clinicians and clinicians in training (fellows) to enable them to pursue innovative projects under the mentorship of MIT faculty and Philips scientific staff. The program will provide funding in return for 50% effort commitment to the project. The program is open to clinicians from the Harvard Teaching Hospitals. Details of the program together with application instructions (including links to participating MIT mentors and laboratories) may be found at https://medicalresearch.mit.edu/clinician_info.cgi. Proposed research should align with at least two of the topic areas within the scope of the award guidelines as outlined on the program website.
 
5. Merck KGaA Darmstadt Germany Biopharma Innovation Cup 2017

Merck KGaA, Darmstadt, Germany, will conduct from June 18-23 2017, the 7th Biopharma Innovation Cup Summer Camp, an initiative offering a chance for advanced students in life sciences, data sciences and business administration programs to attend a one week training program at Merck KGaA, Darmstadt, Germany. This initiative is designed to support the professional development of post-graduate students interested in the pharmaceutical industry and also delivers new innovative approaches covering unmet medical need.

The summer camp is completely free for accepted participants; travel, accommodation and food are paid by Merck KGaA, Darmstadt, Germany!

The Innovation Cup brings together a promising new generation of talent in a meeting of the generations with senior Merck KGaA, Darmstadt, Germany managers and researchers and accomplished retirees. A video showing an overview of the event and statements from previous participants can be viewed here: http://innovationcup.emdgroup.com

Post-graduate students in the life sciences field on their way towards a PhD in biology, medicine, biotechnology, chemistry, bioinformatics, biochemistry, pharmacy, engineering or related fields are invited to apply. In addition, advanced students in data sciences/informatics as well as MBA students or recent MBA graduates with an interest in the pharmaceutical business and a background in life sciences are eligible. Postdocs can apply, too!

Participants have the chance to win with their team the Biopharma Innovation Cup award - EUR 20,000 for the most convincing project plan worked out during the summer camp plus EUR 5,000 for the runner-up.

Applications are accepted from November 1, 2016 to January 31, 2017 at http://innovationcup.emdgroup.com

 
6. Limited Submission Funding Opportunities

We ask that all MGH Investigators interested in applying for any limited submission award submit a Letter of Intent (see detailed instructions below) to the MGH Executive Committee on Research (ECOR) by the deadline indicated for each award to be considered to receive an institutional nomination.

Process
Submit a one- to two-page Letter of Intent (LOI) to the MGH Executive Committee on Research (ECOR) via email to ecor@partners.org.  In addition to your LOI, please include an NIH Biosketch.

The letter of intent should include:

  • Name of the Principal Investigator with appropriate contact information
  • A descriptive title of the potential application
  • Brief description of the project
  • Brief description of why you specifically should be selected to receive institutional nomination for this award

If there is more than one MGH investigator interested in applying for each limited submission award, the LOIs will be used to assess candidates and a review and selection process will take place.

Current Limited Submission Funding Opportunities
Please click here for more information and for our internal deadlines.

  • BD2K Research Education Curriculum Development:  Data Science Overview for Biomedical Scientists (R25)
  • Centers for HIV/AIDS-Related Structural Biology (P50)
  • Alzheimer's Clinical Trials Consortium (ACTC) (U24)
  • NINDS Institutional Center Core Grants to Support Neuroscience Research (P30)
  • T Cell Reagent Research for the Study of Allergic Diseases (U19)
  • Asthma and Allergic Diseases Cooperative Research Centers (U19)

If there is a limited submission funding opportunity you do not see listed above or you have any additional questions, please contact Erin McGivney at 617-643-6471.

 
7. Private Funding Opportunities

Please contact Corporate & Foundation Relations in the Office of Development at devcfr@mgh.harvard.edu if you wish to submit a proposal in response to any of these funding opportunities.  Note that proposals are still routed through the standard InfoEd/Research Management process.

  • Glenn/AFAR Breakthroughs in Gerontology (BIG) Awards, American Federation for Aging Research (AFAR)
  • Request for Education (RFE): Cardiovascular (Non-valvular Atrial Fibrillation [NVAF]), Bristol-Myers Squibb (BMS)
  • Pilot Study Program, Marsha Rivkin Center for Ovarian Cancer Research
  • Scientific Scholar Award, Marsha Rivkin Center for Ovarian Cancer Research
  • Grants, National Pancreas Foundation (NPF)
  • Michael Geisman Fellowships, Osteogenesis Imperfecta (OI) Foundation
  • Pulmonary Function in Adults Living with OI, Osteogenesis Imperfecta (OI) Foundation
  • Health Outcomes - Post Doctoral Fellowships, Pharmaceutical Research and Manufacturers of America Foundation, Inc. (PhRMA Foundation)
  • Health Outcomes - Research Starter Grants, Pharmaceutical Research and Manufacturers of America Foundation, Inc. (PhRMA Foundation)

Please click here for further details on these funding opportunities.

 
8. NIH Update for Week Ending November 4, 2016

For the latest National Institutes of Health notices, requests for applications, and program announcements, follow this link: http://grants.nih.gov/grants/guide/WeeklyIndex.cfm

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In Case You Missed It
 
Reminders of recently posted funding opportunities, deadlines and events

MGH ECOR Formulaic Bridge Funding Support
Application Deadline: 7th day of each month

NIH Loan Repayment Programs (LRPs)
Application Deadline: November 15, 2016

Boston Biomedical Innovation Center (B-BIC) Accepting PILOT & DRIVE Grant Pre-Proposals

How to Communicate Science and Influence People – November 17

Looking for something you saw in a previous Research News release? Check out our archive!

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